1.
School of Medicinal Chemistry, LACDR, University of Leiden, The ...
Since its start in 1992 the LACDR School on Medicinal Chemistry has been an instant success. The 4-days course, hosting some 35 participants only to allow ...
2.
Allosteric modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory ...
3.
Allosteric modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory ...
4.
Division of Medicinal Chemistry, LACDR, University of Leiden, The ...
All four subtypes are studied in our division of Medicinal Chemistry of the Leiden/Amsterdam Center for Drug Research . Ever since 1985 when we started, ...
5.
Inverse agonism
inverse agonism is drug and system dependent; the system may not allow ... Retinitis pigmentosa and congenital night blindness are due to mutations in the ...
6.
Coffee and caffeine
For a medicinal chemist the challenge is to understand the precise mechanism of action of caffeine. Then, we might be able to manipulate the chemical ...
7.
Coffee and caffeine
The only thing caffeine does is "sitting there": it kicks adenosine from the ... the challenge is to understand the precise mechanism of action of caffeine. ...
8.
Allosteric modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory ...
9.
Allosteric modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory ...
10.
Scientific Output
Z.G. Gao, S.K. Kim, A.P. IJzerman, K.A. Jacobson (2005) Allosteric modulation of the adenosine family of receptors. Mini Rev. Med. Chem. 5 , 545-553. ...
